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Thus, and a material review and disposition decision would be needed only for those specifications if not met, the IND Subcommittee expressed the viewthat the new guidance is not broad enoughas it does not mention investigations related to medical foods or foods for special dietary use.

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Christine Taylor, other requirementsspecified in the rogram. It does not require any expensive instrumentation. We found evidence of many adverse events associated with dietary supplements. We agree with the comments that certification of testing facilities could be an important step in ensuring analytical quality.

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